Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
回购股票会帮助推高股价，很多分析师将标准普尔500（Standard & Poor's 500 index）创下多次历史新高归功于股票回购的盛行。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
It will be interesting to see which direction they go at the trade deadline. They have a handful of solid players along with Brook Lopez.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Economists had forecast a 1.5 per cent annual rate, after a 1.6 per cent reading in September. Beijing's inflation target is "around 3 per cent" this year.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
In a statement given to the website Kotaku, Epic Games said the lawsuit was a result of Mr Rogers "filing a DMCA counterclaim to a takedown notice on a YouTube video that exposed and promoted Fortnite Battle Royale cheats and exploits."
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Together, the world’s 10 highest-paid actresses tallied a combined $205 million between June 1, 2015 and June 1, 2016, before management fees and taxes, Forbes said.
That was in line with last month’s manufacturing PMIs, which showed an uptick in sector activity,
Trends and targets in antiviral phototherapy
The most exciting part is the offseason
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
1号 what the fuck: “职场辣妈”的新境界
Novel biosensing methodologies for ultrasensitive detection of viruses
7. Cannes' 'year of women' didn't go so well
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
"There are 1,400 individuals who are involved in the departures for jihad,for terrorism, in Syria and in Iraq," Valls told BFMTV.
Yunge from the Desert is based on an online novel with the same title by Tong Hua. It is about love triangle of a girl named Yunge, a nobleman, and the emperor in the Han (206BC-220AD). Nearly premiering in the same month as Nirvana in Fire, Yunge was much outflanked by the latter. It was criticized for its poor knowledge of history. To some audiences, charming Angela Baby herself became the only appeal of the adaptation.
ACE2 as a potential therapeutic target for pandemic COVID-19
200911/88512.shtmlThe price of Chinese zodiac stamps commemorating the 1980 Year of the Monkey have rocketed to a historical high for a number of reasons, according to National Business Daily.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Take the intriguing reintroduction of “unfeigned regards” — last big in the 18th century and now found on emails from Indian help centres. But the winning sign-off, at the bottom of a message sent one Friday, was: “weekend well”. I nearly awarded it second prize for the best noun pretending to be a verb, though at the last minute this award was snatched by a consultant overheard saying: “Can we cold towel that?”
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
But closing the deal on RCEP less than a year after Donald Trump pulled the US out of the TPP would be a big win for Beijing.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Andersl?v, Sweden was plagued by residents with green hair. Johan Pettersson discovered that there was too much copper in their water.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
They expect the heat to get much worse over coming decades, but already it is killing forests around the world, driving plants and animals to extinction, melting land ice and causing the seas to rise at an accelerating pace.
In an effort to protect China's role in the global economy as a manufacturing hub, the central bank devalued the currency in August, in the biggest drop in decades. Later in the year, after the International Monetary Fund added the renminbi to its group of global reserve currencies, the value of the currency fell further, possibly reflecting capital outflows.
Influenza neuraminidase: A druggable target for natural products
In an emailed statement, FIFA said that during group stage matches, it sold a total of 143,364 of the cheapest tickets, which amounted to roughly 3,000 such tickets available per match.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
HOUSE OF CARDS (Netflix, Feb. 27) Netflix’s political grand guignol gets a 13-episode third season. Kim Dickens of “Treme” joins Kevin Spacey and Robin Wright in the cast, and two members of Pussy Riot will make a guest appearance.
LONDON — In the 1970s, the British comedian Tommy Cooper used to tell a joke about asking an auction house to value a violin and a painting that he had discovered in an attic. The good news, he was told, is that they were made by Stradivarius and Rembrandt. The bad news was that the painting was by Stradivarius and the violin was by Rembrandt.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Among the 772 movies made in China in 2016, 43 of them reached a box office of over 100 million yuan. Chinese movies harvested an overseas box office of 3.8 billion yuan in 2016 with a yearly increase of over 38%.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
“…was asked ttell the interviewer a little about herself, and didn’t have anything tsay.”
But, when the skeletal remains were analyzed, the researchers found that the tombs had been reused multiple times. Some of the tombs contain more than 10 occupants, and the"repeated multiple burials warrant further study," the researcherswrote.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The two extraordinary sex toys will go on display at an upcoming exhibition at the Asian Art Museum of San Francisco in the United States.
The school is also second for its international course experience. More than four in five of its latest graduating cohort went on an internship abroad and over half studied in another country for more than a month.
So far this year, companies have announced 376 share-repurchase initiatives for a total of $261 billion, according to data from Birinyi Associates. That's nearly 72% higher than 2012, though slightly lower when compared to the same period in 2013, which was a record year for buybacks.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
4. Mark Turner Quartet “Lathe of Heaven” (ECM) On his first proper album as a leader in 13 years, the tenor saxophonist Mark Turner favors slithery interplay with the trumpeter Avishai Cohen, and finds new purpose in post-bop protocols. There’s dry intrigue in his compositions, and supple exactitude in his rhythm team: Joe Martin on bass, Marcus Gilmore on drums.
There's a difference, though, in a team like Miami that's playing its young guys and trying to build a core while taking on losses, and, say, the Magic, who are trying to jump-start a stalled process.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Although it looked like the mobile patent wars might cool off after several settlements late in 2014, this year kicked off with a skirmish between Apple and Ericsson over patent royalties related to wireless communications. BlackBerry used to be pretty litigious: It even took on celebrity Ryan Seacrest over its keyboard! But these days it is more focused on trying to convince smartphone buyers that its technology is cool again. Or at least relevant.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Dawn Hudson, Academy CEO:
“We weren’t looking to throw the bums out, as they might say about an election. We were just really impressed with a flood of new powertrains, ” says Drew Winter, WardsAuto World Editor-in-Chief. “What was great yesterday might be less impressive tomorrow because engine technology is changing so rapidly.”
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Harry Styles, 'Harry Styles'
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Sweden’s Proponent of ‘Feminist Foreign Policy,’ Shaped by Abuse
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Third, McDermott provides some protection against the possibility of Andre Roberson departing as a free agent in the summer.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
If it isn't appropriate to interrupt, make a quick note of your question so you don't forget, and ask later.
We will continue to transform government function.
'Chinese clients are not only buying in Asia but in New York and Geneva as well.'
Stock pickers encountered difficulty this year in part because of concentration at the top of the market. Just five stocks—Apple, Berkshire Hathaway, Johnson & Johnson, Microsoft, and Intel— accounted for 20% of the market’s gains. If you weren’t at least equally weighted toward them, you had virtually no shot at making up for missing their enormous, index-driving gains. A majority of the market’s stocks did not perform nearly as well. According to the Leuthold Group, only 30% of S&P 1500 stocks posted gains exceeding the index itself. You’d have to go back to 1999 to see anything like this.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Emissions have been falling gradually in recent years in most of the developed countries, in part because of economic weakness but also because of strengthening climate policies. Emissions in the 28-nation European Union fell 1.8 percent in 2013, despite increases in coal consumption in a few countries, including Germany and Poland. Emissions decreased sharply in Britain, Italy and Spain.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Though Hand was British Petroleum's SVP of Global Brand, Marketing and Innovation, for several years, she's on a much more environmentally friendly mission today. Project Frog aims to revamp the construction industry with simple-to-build spaces (they takes days, rather than months to construct) that consume about 50% less energy than traditional buildings for sectors like education and healthcare. Hand's plan seems to be working: revenue is expected to more than double this year.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
n. 人口 ，(全体)居民，人数
States are falling all over themselves to be chosen as the site for Tesla’s proposed $5 billion Gigafactoryto produce lithium ion batteries. California is competing with Nevada, Arizona, New Mexico, and Texas, and the bidding for the factory, which could employ up to 6,500 people, is said to be up to $500 million.
里尔宁援引了荷兰经济政策分析局(CPB Netherlands Bureau for Economic Policy Analysis)的最新数据，数据显示，9月至10月经季节性调整的全球贸易量下降了1.1%，他表示，去年将被证明是世界贸易自2009年以来表现最糟糕的一年。
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
?Women fall for him because he's exciting to be around and this plays a much larger part in a relationship than most think. It's the key to a great first date. Even the femme fatales assigned to kill Bond fall for him. But studies show this isn't surprising at all. 007's character has frequently been accused of being sexist. This is probably true -- and only serves to make him that much more attractive to the ladies.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
The Great American Eclipse
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
n. 没精打采的样子，耷拉，笨人 v. 没精打采地站，坐
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Bond King Bill Gross admits, 'QE must end.' Trillions of cheap money 'has distorted incentives and inflated asset prices to artificial levels.' But now Gross says 'the Fed plan may be too hasty.'
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
May your New Year be filled with special moment, warmth, peace and happiness, the joy of covered ones near, and wishing you all the joys of Christmas and a year of happiness.愿你的新年充满温馨，祥和，与亲人团聚的快乐，祝乐陶陶，新年乐无限。
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
"Pandas used to be really difficult to breed in captivity, but the Chengdu base and other zoos around the world have cracked the problem and now there are around 400 in captivity," Mr Marven said.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Inflation (and deflation) won't rear its ugly head Surging oil production — along with slower global growth — has caused the price of petroleum to collapse from more than $100 a barrel last summer to barely $50 a barrel at the end of 2014. The effect has been to reverse an uptick in U.S. inflation earlier in the year.
A facile assay for rapid detection of COVID-19 antibodies
Media reports from both countries, which have been involved in rising tensions over territories in the South China Sea, lay the blame on the their respective governments for illegal foods entering their markets.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
An employee in the public relations department at Tencent Holdings, operator of a live-broadcast app through which a man received online payments of more than 250,000 yuan ($36,400) from a 13-year-old girl for his singing talent, said the girl might have faked her age when registering.
The work suits Carlson who has been into singing and musical theater her whole life.
"There are 1,400 individuals who are involved in the departures for jihad,for terrorism, in Syria and in Iraq," Valls told BFMTV.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
If a sitcom that lasts for 10 years is considered popular, then surely one that still stirs up emotions after 20 must be considered a classic. Friends first aired in the US in 1994, featuring a cast of six young men and women in New York. In the time since, it’s become one of the most famous titles in the sitcom genre, aired in over 100 countries and regions in the world.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Google's brand is now worth more than 109 billion U.S. dollars, around 2 billion dollars more than Apple, making it the most lucrative in the world.
CELEBRITY couple Ronald Cheng and Charlene Choi, who announced their separation earlier, are actually getting a divorce。 明星情侣郑中基和蔡卓妍，早先宣布二
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
2. Wells Fargo
Huawei, the Chinese technology group, has taken market share from both Apple and Samsung, according to BrandZ.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Skeptics of climate change have long argued that global warming stopped around 1998, when an unusually powerful El Ni?o produced the hottest year of the 20th century. Some politicians in Washington have seized on that claim to justify inaction on emissions.
Anti-HIV drug repurposing against SARS-CoV-2
批评人士一直急于指出，库克对新产品开发的参与度不如他前任那样高，而且当他走上舞台介绍新品时，也无法引起同样的兴奋。但库克知道自己的短处，他从健身和时尚界招揽人才，组建了一支新团队，其中包括前博柏利(Burberry)首席执行官安杰拉?阿伦茨(Angela Ahrendts)，以及工业设计师马克?纽森(Marc Newson)。
Length-scale dependence of protein hydration-shell density
As a result, business investment in key areas such as equipment has been historically weak for a U.S. recovery. A slowly improving jobs picture and rising household wealth could spark a virtuous cycle of stronger consumer spending, increased business confidence and rising investment. If it doesn't, the year could be another letdown.
At 36, women are about two years younger than men but senior positions are fairly well distributed between genders, with only slightly more women in relatively junior positions — 26 per cent of them are professionals compared with 24 per cent of men.
"Compared with previous years, this year's two sessions are due to see the new leadership elected, and reforms of organizations will be discussed. They will also elaborate on detailed plans for implementing policies proposed by the 18th National Congress of the Communist Party of China."
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
最佳迷你剧/电影：《美国罪案故事：公诉辛普森》(“The People v. O. J. Simpson: American Crime Story”, FX)
About this collection
“Brands that are known for going it alone are partnering with unexpected allies,” Gilbert says. “If you dig into Apple’s investment, the special projects team reads like a who’s who list of some of the best talent in the world coming from every sector imaginable.”
After year of stars such as Salma Hayek and Gwyneth Paltrow claiming to be vistims of harassment, McGowan has said she understands why Donald Trump supporters hate Hollywood, whose apparent liberalism she says is fake.